Table 1 Summary of the previous literature in pedunculated focal nodular hyperplasia
Author/year of publication | Sex/age (years) | Symptoms | Size | Location | Laboratory | Imaging | Treatment | Follow-up | Chronic OCP usage |
|---|---|---|---|---|---|---|---|---|---|
Sawhney et al. (1991) [18] | Female/12 | Asymptomatic | N/A | Left lobe of the liver | N/A | US and CT | Surgery | N/A | No |
Byrnes et al. (2004) [9] | Female/30 | RUQ pain | Multiple lesions (the largest one was 16 cm × 18 cm) | Seg 3, 4B | Normal | Noncontrast MRI and CT angiogram | Surgery | No complications | No But she was pregnant |
Wasif et al. (2008) [2] | Female/48 | RUQ pain | 3.2 cm × 2.4 cm × 2.4 cm | Seg 4B | Normal | US and CT | Surgery | No recurrence | No |
Khan et al. (2011) [17] | Female/29 | Abdominal pain and emesis | 19.5 cm × 15.8 cm × 9.5 cm | Seg 3, 4B | Anemia and elevated liver enzymes | CT | Surgery | No recurrence | No |
Badea et al. (2014) [14] | Female/29 | Abdominal pain | 8 cm × 5 cm | Seg 5 | Normal | US, CEUS, and CT | Laparoscopic resection of the mass and gall bladder | No complications | Yes |
Reddy et al. (2015) [12] | Female/35 | Chronic abdominal pain | 2.89 cm × 2.7 cm | Seg 3 | N/A | CT and EUS | Laparoscopic resection | N/A | N/A |
Zeina et al. (2016) [15] | Female/25 | Epigastric pain and nausea | 4.8 cm | Seg 2 | Normal | US, CT, and MRI with scintigraphy using gadobenate dimeglumine | N/A | N/A | No |
Zhuang et al. (2016) [19] | Male/6 | Asymptomatic | 10.5 cm × 9.9 cm | Right hepatic lobe | Normal | US and CT | Surgery | No complications | No |
Kinoshita et al. (2017) [16] | Male/32 | Asymptomatic | 8 cm | Seg 4, 5 | Elevated CRP, WBC, AST, and ALT | CT, MRI, and in the readmission due to rupture of the lesion a hepatic angiography was also done | Conservative management at first but due to rupture of the lesion patient underwent surgery | No complication after surgery | No |
Koolwal et al. (2018) [7] | Female/3 | Abdominal distension | 5.9 cm | Right hepatic lobe | Normal | US, CT, and MRI | Surgery | N/A | No (history of preterm birth) |
Martiniuc et al. (2018) [13] | Female/40 | Asymptomatic | 4.2 cm × 5 cm | Seg 3 | Normal | US and contrast enhanced CT | Surgery | No complications | No |
Navarini et al. (2020) [6] | Female/26 | Acute abdomen and a palpable mass in the epigastrium | 13 cm × 7 cm | Left hepatic lobe | N/A | MRI | Surgery | N/A | N/A |
Alfayez et al. (2021) [5] | Male/5 | RUQ pain | 9 cm × 10 cm × 12 cm | Seg 5, 8 | Normal | US, CT, and MRI | Surgery | No complications | No |
Ismail et al. 2021 [10] | Female/38 | Asymptomatic | 4.5 cm × 3.5 cm × 3 cm | Seg 3 | Normal | N/A (detected intraoperatively during surgical repair of hernia) | Surgery | No recurrence | Yes |
Akaguma et al. (2023) [20] | Female/35 | RUQ abdominal pain | 7 cm × 7 cm × 5 cm | Seg 6 | N/A | US and CT | Surgery | No complication | Yes |