Fig. 2
From: Metastasis of serous ovarian carcinoma to the breast: a case report and review of the literature
Histopathological sections and immunochemistry demonstrating metastatic ovarian high-grade serous carcinoma. A Histologic sections of the left ovary with infiltrative tumor cells in the ovarian stroma (arrowhead, H&E stain at 5x). B On higher magnification, the tumor cells are large with hyperchromatic nuclei (arrowhead, H&E stain at 20x). C The tumor cells are immunoreactive for PAX-8 (immunohistochemical stain with a brown chromogen, 20x). D Histologic sections of the right breast with infiltrative tumor cells (arrowhead, H&E stain at 5x). E On higher magnification, the tumor cells are morphologically similar to the patient’s ovarian tumor (arrowhead, H&E stain at 20x). F PAX-8 immunohistochemical stain with brown chromogen highlights the tumor cells, confirming the diagnosis of metastatic ovarian high-grade serous carcinoma (20x)