Fig. 2From: Hepatic and lung methotrexate-associated polymorphic lymphoproliferative disorders arising during postoperative follow-up of renal cell carcinoma: a case reportPathological appearance of lung biopsy specimen. Variously sized lymphoid cells proliferated diffusely (A, B), and necrotic areas were observed (A, arrows) by hematoxylin and eosin staining. Lymphoid cells are positive for CD20 (C), and cCD3-positive cells are observed in the background (D) by immunohistochemistry. Positive EBER signals were also observed using in situ hybridization (E). Bars: 100 μm (A), 50 μm (B–E)Back to article page