Fig. 2

Microphotographs of the ovary tumor (A, B) and cerebellar lesion (C, D), hematoxylin–eosin stains; 4× magnification (A, C) and 10× magnification (B, D). A Glandular and papillary patterns of high-grade serous carcinoma with significant nuclear pleomorphism. B Solid appearance of high-grade serous carcinoma with significant nuclear atypia, eosinophilic cytoplasm and high mitotic index. C, D Poorly differentiated adenocarcinoma with papillary aspects. E, F Immunohistochemical stains of cerebellar lesion, witch suggested the secondary origin of the lesion from an ovarian primary: cytokeratin 7 (CK7) (E), β-catenin (β-cat) (F), and estrogen (Estrog) (G)