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Gonococcus infection probably acquired from bathing in a natural thermal pool: a case report

Abstract

Background

Authorities need to recognize that, while rare, gonorrhea can be transmitted nonsexually, and should not be presumed definitive evidence of abuse. We report the unusual case of a girl diagnosed with Neisseria gonorrhoeae after bathing in a heavily frequented hot pool at the edge of the crater lake Specchio di Venere (“Mirror of Venus”) on Pantelleria Island, Italy.

Case presentation

Two days after bathing in the pool, this 11-year-old Austrian girl developed vulvovaginitis that partially settled with antifungal cream. Subsequent swabs cultured positive for Neisseria gonorrhoeae. Family members tested negative. The child adamantly denied any sexual contact, and no opportunities for sexual exposure could be identified. It was therefore concluded that she must have acquired the infection from pool water contaminated by gonococcus after a 2-day incubation period. The infection was successfully treated with ceftriaxone and azithromycin with no adverse effects.

Conclusions

The pools are shallow, close to body temperature, isotonic, slightly acidic from CO2 bubbles, and contain organic particles, all potentially supporting survival of gonococcus. There are historical case reports in the literature of gonococcal epidemics in children’s hospitals being traced to common baths. It is imperative that all cases of gonococcal infection in children are fully investigated, including examining all other relevant family members, to determine whether sexual assault has occurred. This is not a diagnosis to be missed. However, both sexual and nonsexual transmission are possible. A presumption that a gonococcal infection is diagnostic of sexual abuse can be dire, with children wrongfully removed from their parents’ care, and their caregivers facing false charges of sexual crimes. Our case serves to illustrate that the very uncommon diagnosis of gonorrhea in a child may be the result of nonsexual transmission of the infection, and that contaminated hot pools are a very rare source of infection that should be considered.

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Background

Neisseria gonorrhoeae colonizes human mucosa, including conjunctiva, oropharynx, urethra, and anorectal tissues. Untreated, it may ascend into the female upper genital tract or into the male prostate and testis, and rarely, disseminated infection occurs in the form of septicemia or arthritis. While in adolescents and adult women the initial genital infection involves the cervix, prepubertal girls are susceptible to gonococcal vulvovaginitis. This is because the prepubertal vagina is slightly acidic to slightly alkaline (pH 6.5–7.5) with a thin atrophic mucosa. Postpubertal estrogenization produces a more acidic (pH 3.5–4.5) and keratinized vaginal epithelium, resistant to gonococcal colonization [1].

Gonococcus flourishes at 25–39 °C and is vulnerable to drying. Conditions for its optimal growth include humidity > 90%, isotonic environment, and 5–7% carbon dioxide at 36 °C [2]. In vitro experiments have cultured gonococcus from inoculated fabrics (towels and sheets) and other materials after at least several hours [3,4,5,6]. While gonococcal infection is predominantly sexually transmitted, numerous cases of accidental nonsexual transmission from autoinoculation, fomite transfer, or bathing in contaminated water are reported [3]. In individual cases, the possibility of sexual transmission cannot be excluded; however, the totality of the evidence is compelling support of occasional nonsexual transmission.

The aim of this paper is to report an unusual case of nonsexual transmission of gonorrhea probably acquired from bathing in a contaminated natural thermal hot pool.

Case presentation

In August 2020, an 11-year-old Austrian girl visited the crater lake Specchio di Venere (“Mirror of Venus”) on Pantelleria Island, Italy with her parents and 7-year-old sister. After swimming in the lake, she spent an hour soaking in one of the hot pools at the lake’s edge (Fig. 1). She was lying in a pool about 20 cm deep and did not rinse off after leaving.

Fig. 1
figure 1

(Permission to reproduce photograph provided by Onemag.it)

The shallow hot-spring pools created by stone walls on the edge of Lake Specchio Di Venere, Pantelleria Island, Italy

The pools are a major tourist attraction and are heavily used. There were five pools, with up to five people per pool, both adults and children, and frequent coming and going, with people waiting for a space to be vacated. The girl and her father were never alone in the pool. Her younger sister bathed in a different pool with her mother.

Two days after bathing in the pool, the girl developed vulvovaginal burning and discharge. The burning kept her from swimming in the sea for a couple of days, which caused disappointment whenever she tried to enter the water. Her symptoms partly settled but did not completely resolve with the use of antifungal cream purchased over the counter. The family returned to their home country Austria 2 weeks later, and she was then was seen by her pediatrician. She had no signs of sepsis, with no elevated temperature or pulse. Vaginal examination was normal, but a vaginal swab returned a positive aerobic culture for Neisseria gonorrhoeae. A second swab taken the following week confirmed the diagnosis of gonococcal vulvovaginitis. The parents and the younger sister were tested for gonorrhea with negative results (see Fig. 2 for the case timeline).

Fig. 2
figure 2

Case timeline

The possibility of sexual transmission was explored. The child adamantly denied any sexual contact. The family had been traveling together on holiday when the symptoms started, and there was no evidence or opportunity identified for sexual transmission. It was therefore concluded that she must have acquired the infection from pool water contaminated by gonococcus after a 2-day incubation period [7].

Once the diagnosis was established and the illness explained to her, her first reaction was fear that her new classmates might hear about this infection, as she had started high school immediately upon arrival in her hometown. The stress of adjusting to a new school coupled with the infection led to crying and fatigue, particularly just before treatment, as she was very afraid of the infusion.

However the pediatrician was gentle, both parents were present during treatment, and she coped well. She was treated with ceftriaxone infusion 50 mg/kg body weight followed by oral azithromycin 500 mg the next day. Her pediatrician also advised whey baths for 2 weeks to help restore her vaginal flora. Her vaginal symptoms settled within a couple of days. She experienced slight anorexia and loose stools for a couple of days post-treatment, but then made a full recovery. After being treated, she adapted well to her new school environment.

A repeat swab 4 weeks later was negative. Slight delays in getting swabs taken and treatment initiated occurred because the country was reentering lockdown for coronavirus disease 2019 (COVID-19), as well as the school year starting under pressure because of the imminent lockdown. She made an uneventful recovery and remains well.

Discussion

We report the case of gonococcal vulvovaginitis in an 11-year-old prepubertal Austrian girl almost certainly contracted from bathing in a contaminated hot pool. It is imperative that all cases of gonococcal infection in children are fully investigated, including examining all other relevant family members, to determine whether sexual assault has occurred. This is not a diagnosis to be missed. However, both sexual and nonsexual transmission is possible. The consequences of the presumption that a gonococcal infection must be diagnostic of sexual abuse can also be dire, with children wrongfully removed from their parents’ care, and their caregivers facing false charges of sexual crimes.

The Specchio di Venere pools are shallow, murky, glass-green-colored from algae, and almost stagnant, although some water exchange occurs through the loosely stacked boulder walls. Hot water and gas bubbles (98% CO2) enter the pools through small holes in the sediment. Gradients in temperature develop within the pools from the source of the springs (> 40 °C) to where they mix with the lake water at the pools’ edges (~ 37°). Hence, the water is near body temperature, slightly acidic (pH 6.3–6.9), and closely isotonic (conductivity of 14–17 mS/cm at 25 °C), and contains mineral and organic particles as potential substrates for biofilms [8,9,10], potentially increasing the survival of gonococcus.

Prior to the advent of antibiotics, the source of gonorrhea epidemics in children’s hospitals was traced to common baths [11,12,13], as well as to towels, wash rags, diapers, bandages, bed linens, instruments, and children’s hands [13,14,15,16,17,18,19,20,21,22,23,24]. Epidemics of gonococcal conjunctivitis continue to occur in rural African and Australian aboriginal communities, thought to be mediated by flies, dirty fingers, and face cloths [25,26,27]. Case reports and cases series of probable household nonsexual transmission from sharing towels, clothes, and beds are also reported, from an index sexually transmitted case [28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49]. Unusual cases of nonsexual transmission include autoinoculation from a contaminated public toilet seat in an 8-year-old girl [50], and transmission from intercourse with an inflatable doll [51]. We report a case of vulvovaginal nonsexual transmission. This was presumably acquired from bathing in a shallow thermal pool frequented by many tourists, which is more likely than from using a public toilet. Hot pools have been recognized as sources of various serious infections [16, 17]. This rare event is likely due to a number of unique factors, including the timing of the child’s bathing in relation to that of an infected visitor, but those using these pools need to be alerted to the possibility of such exposure, including the risk of possible conjunctival infection, on occasion. It would be valuable to conduct experiments whereby water from the pools is inoculated with Neisseria gonorrhoeae, the temperature and CO2 aeration maintained, and then assays conducted to see if gonococcus can be cultured at different durations following inoculation, but this is beyond the scope of these authors.

There needs to be public understanding that people bathing in heavily frequented shallow thermal pools risk exposure to pathogens through inoculation by other bathers, including Neisseria gonorrhoeae, but also fecal contaminants such as Escherichia coli and Pseudomonas sp. We suggest provision of a shower and antibacterial soap near the hot springs. A sign should make visitors aware of strict hygiene before entering the pools.

The strength of this case report is that it adds to the literature by reporting a case of nonsexual transmission of Neisseria gonorrhoeae causing vulvovaginitis in a prepubertal child. The report draws on many other cases of nonsexual transmission reported in the literature, plus empirical published data demonstrating that the temperature, pH, and tonicity of the pools in question provide an environment in which gonococci might flourish. The case weakness is that, inevitably, it is impossible to prove that the pool was the definitive source of infection.

Gonococcal infections in prepubertal children occur very infrequently. Acquisition from sexual abuse must always be the first consideration, and should be investigated as a cause. However, authorities are reluctant to acknowledge that the mode of transmission may also be nonsexual, and that the infection is not definitive evidence of sexual assault. National guidelines may state that gonococcal infection in prepubertal children is always, or almost always, diagnostic of sexual abuse, without any discussion of possible nonsexual modes of transmission [7, 52, 53]. In her role as forensic physician, the lead author has encountered cases of nonsexually transmitted genital gonorrhea in prepubertal girls in Australia, New Zealand, the USA, Canada, and Denmark, where the child abuse authorities inform the courts that transmission can only be through some form of sexual activity with mucous membrane to mucous membrane contact. These cases include probable transmission from an infected mother using a towel to dry herself and then her 3-year-old daughter; an infected father sharing a towel with his 3-year-old daughter, and an 8-year-old girl using a wash cloth and towel immediately after her infected father had used them.

Conclusion

Our case serves to illustrate that the very uncommon diagnosis of gonorrhea in a child may be the result of nonsexual transmission of the infection, as well as sexual, and that contaminated hot pools are a very rare source of infection that should be considered.

Availability of data and materials

Not applicable.

References

  1. Brabin L, Roberts SA, Fairbrother E, et al. Factors affecting vaginal pH levels among female adolescents attending genitourinary medicine clinics. Sex Transm Infect. 2005;81(6):483. https://0-doi-org.brum.beds.ac.uk/10.1136/sti.2005.014621.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Woods CR. Gonococcal infections in neonates and young children. Semin Pediatr Infect Dis. 2005;16(4):258–70.

    Article  Google Scholar 

  3. Goodyear-Smith F. What is the evidence for non-sexual transmission of gonorrhoea in children after the neonatal period? A systematic review. J Forensic Legal Med. 2007;14(8):489–502.

    Article  Google Scholar 

  4. Srivastava AC. Survival of gonococci in urethral secretions with reference to the nonsexual transmission of gonococcal infection. J Med Microbiol. 1980;13(4):593–6.

    Article  CAS  PubMed  Google Scholar 

  5. Gilbaugh JH Jr, Fuchs PC. The gonococcus and the toilet seat. N Engl J Med. 1979;301(2):91–3.

    Article  PubMed  Google Scholar 

  6. Perez JL, Gomez E, Sauca G. Survival of gonococci from urethral discharge on fomites. Eur J Clin Microbio Infect Dis. 1990;9(1):54–5.

    Article  CAS  Google Scholar 

  7. Gonorrhoea Guideline Writing Group. New Zealand Guideline for the management of gonorrhoea, 2014, and response to the threat of antimicrobial resistance. New Zealand: New Zealand Sexual Health Society; 2014. p. 61.

    Google Scholar 

  8. Azzaro E, Badalamenti F, Dongarrà G, et al. Geochemical and mineralogical studies of Lake Specchio di Venere, Pantelleria Island, Italy. Chem Geol. 1983;40(1–2):149–65.

    Article  CAS  Google Scholar 

  9. Aiuppa A, D’Alessandro W, Gurrieri S, et al. Hydrologic and geochemical survey of the lake ‘Specchio di Venere’ (Pantelleria island, Southern Italy). Environ Geol. 2007;53(4):903–13.

    Article  CAS  Google Scholar 

  10. Dongarrà G, Hauser S, Alaimo R, et al. Hot waters on Pantelleria island. Geochemical features and preliminary geothermal investigations. Geothermics. 1983;12(1):49–63. https://0-doi-org.brum.beds.ac.uk/10.1016/0375-6505(83)90040-8.

    Article  Google Scholar 

  11. Skutsch. Vulvo-vaginitis gonorroeica bei kleinen Mädchen. Jena. 1891.

  12. Succhard. Rev Mens Des Mal De L'Enfant. 1888;6:265.

  13. Sheffield H. Contribution to the study of infectious vulvo-vaginitis in children, with remarks upon purulent ophthalmia, and a report of sixty-five cases. Am Medico-Surg Bull. 1896;9(30 May):726–31.

    Google Scholar 

  14. Czeri. Wien Med Wochnschr. 1885;35:352.

  15. Baer J. Epidemic gonorrheal vulvo-vaginitis in young girls. J Infect Dis. 1904;1(19 March):313.

    Article  Google Scholar 

  16. Kimball RB. Gonorrhoea in infants, with a report of eight cases of pyremia. NMZ Med Rec. 1903;64:761.

    Google Scholar 

  17. Koplik H. Prophylactic measures to prevent the spread of vulvovaginitis in hospital services. Arch Ped. 1903;10:735–41.

    Google Scholar 

  18. Skiba-Zaborowska M. Eine Epidemie von vulvo vaginitis kleiner Mädchen. Zurich. 1898.

  19. Welt-Kakels S. Vulvovaginitis in little girls: a clinical study of 190 cases, part 1. NY Med J Phila Med J. 1904;80(8 Oct):689–93.

    Google Scholar 

  20. Cotton A. An epidemic of vulvovaginitis among children. Arch Ped Adolesc Med. 1905;22(Feb):3106–15.

    Google Scholar 

  21. Hamilton A. Gonorrheal vulvovaginitis in children with special reference to an epidemic occurring in scarlet fever wards. J Infect Dis. 1908;5:133–57.

    Article  Google Scholar 

  22. Holt L. Gonococcus infections in children, with especial reference to their prevalence in institutions and means of prevention. NY Med J Phila Med J. 1905;81(18 March):589–93.

    Google Scholar 

  23. Cooperman M. Gonococcus arthritis in infancy. Am J Dis Child. 1927;33:932.

    Article  Google Scholar 

  24. Seippel C. Venereal diseases in children. Ill Med J. 1912;22(July):50–6.

    Google Scholar 

  25. Matters R. Non-sexually transmitted gonococcal conjunctivitis in Central Australia. Commun Dis Intell. 1981;13:3.

    Google Scholar 

  26. Matters R, Wong I, Mak D. An outbreak of non-sexually transmitted gonococcal conjunctivitis in Central Australia and the Kimberley region. Commun Dis Intell. 1998;22(4):52–6 (discussion 57-8).

    CAS  PubMed  Google Scholar 

  27. Mikru FS, Molla T, Ersumo M, et al. Community-wide outbreak of Neisseria gonorrhoeae conjunctivitis in Konso district, North Omo administrative region. Ethiop Med J. 1991;29(1):27–35.

    CAS  PubMed  Google Scholar 

  28. Allue X, Rubio T, Riley HD Jr. Gonococcal infections in infants and children. Lessons from fifteen cases. Clin Pediatr. 1973;12(10):584–8.

    Article  CAS  Google Scholar 

  29. Burry VF, Thurn AN. Gonococcal infections in prepubertal children. Mo Med. 1971;68(9):691–2.

    CAS  PubMed  Google Scholar 

  30. Doyle JO. Accidental gonococcal infection of the eyes in children. Br Med J. 1972;1(792):88.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  31. Doyle JO. Accidental gonococcal infection of a child’s eye. Unusual source of infection. Br J Vener Dis. 1974;50(4):315–6.

    CAS  PubMed  PubMed Central  Google Scholar 

  32. Shore WB, Winkelstein JA. Nonvenereal transmission of gonococcal infections to children. J Pediatr. 1971;79(4):661–3.

    Article  CAS  PubMed  Google Scholar 

  33. Auman GL, Waldenberg LM. Gonococcal periappendicitis and salpingitis in a prepubertal girl. Pediatrics. 1976;58(2):287–8.

    CAS  PubMed  Google Scholar 

  34. Felman YM, Nikitas JA. Gonococcal infections in infants and children. Medical and epidemiologic considerations. NY State J Med. 1979;79(7):1063–5.

    CAS  Google Scholar 

  35. Felman YM, William DC, Corsaro MC. Gonococcal infections in children 14 years and younger. Epidemiologic and other lessons drawn from a survey of 30 instances. Clin Pediatr. 1978;17(3):252–4.

    Article  CAS  Google Scholar 

  36. Folland DS, Burke RE, Hinman AR, et al. Gonorrhea in preadolescent children: an inquiry into source of infection and mode of transmission. Pediatrics. 1977;60(2):153–6.

    CAS  PubMed  Google Scholar 

  37. Frewen TC, Bannatyne RM. Gonococcal vulvovaginitis in prepubertal girls. Clin Pediatr. 1979;18(8):491–3.

    Article  CAS  Google Scholar 

  38. Low RC, Cho CT, Dudding BA. Gonococcal infections in young children. Studies on the social, familial, and clinical aspects of 11 instances. Clin Pediatr. 1977;16(7):623–6.

    Article  CAS  Google Scholar 

  39. Osoba A, Alausa K. Vulvovaginitis in Nigerian children. Niger J Paediatr. 1974;1:26–32.

    Google Scholar 

  40. Reynolds V, Oates JK, Newsom SW. Prepubertal gonococcal vulvovaginitis: a penicillin-resistant infection treated with cefotaxime. Lancet. 1979;2(8135):206–7.

    Article  CAS  PubMed  Google Scholar 

  41. Tunnessen WW Jr, Jastremski M. Prepubescent gonococcal vulvovaginitis. Clin Pediatr. 1974;13(8):675–6.

    Article  Google Scholar 

  42. Alausa KO, Osoba AO. Epidemiology of gonococcal vulvovaginitis among children in the tropics. Br J Vener Dis. 1980;56(4):239–42.

    CAS  PubMed  PubMed Central  Google Scholar 

  43. Alexander WJ, Griffith H, Housch JG, et al. Infections in sexual contacts and associates of children with gonorrhea. Sex Transm Dis. 1984;11(3):156–8.

    Article  CAS  PubMed  Google Scholar 

  44. Dada-Adegbola HO, Oni AA. Review of cases of children with gonorrhoea—source of infection. Afr J Med Med Sci. 2001;30(4):347–51.

    CAS  PubMed  Google Scholar 

  45. Ingram DL, White ST, Durfee MF, et al. Sexual contact in children with gonorrhea. Am J Dis Child. 1982;136(11):994–6.

    CAS  PubMed  Google Scholar 

  46. Ismail R, Toh CK, Ngeow YF. Gonococcal vulvovaginitis among female children in Malaysia. Sex Transm Dis. 1985;12(3):114–6.

    Article  CAS  PubMed  Google Scholar 

  47. Lewis LS, Glauser TA, Joffe MD. Gonococcal conjunctivitis in prepubertal children. Am J Dis Child. 1990;144(5):546–8.

    CAS  PubMed  Google Scholar 

  48. Meek JM, Askari A, Belman AB. Prepubertal gonorrhea. J Urol. 1979;122(4):532–4.

    Article  CAS  PubMed  Google Scholar 

  49. Nair P, Glazer-Semmel E, Gould C, et al. Neisseria gonorrhoeae in asymptomatic prepubertal household contacts of children with gonococcal infection. Clin Pediatr. 1986;25(3):160–3.

    Article  CAS  Google Scholar 

  50. Dayan L. Transmission of Neisseria gonorrhoeae from a toilet seat. Sex Transm Infect. 2004;80(4):327.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  51. Kleist E, Moi H. Transmission of gonorrhoea through an inflatable doll. Genitourin Med. 1993;69(4):322.

    CAS  PubMed  PubMed Central  Google Scholar 

  52. Committee on Child Abuse and Neglect. Gonorrhea in prepubertal children. Pediatrics. 2020;101(1):134–5. https://0-doi-org.brum.beds.ac.uk/10.1542/peds.101.1.134.

    Article  Google Scholar 

  53. Public Health. Communicable Disease Management protocol—Gonorrhea. Canada, 2015:18.

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Acknowledgements

Thanks to Dr. Ulrike Girardi, Salzburg, Austria for her assistance in this case.

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This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Both authors have made substantial contributions to the conception and design of the study, interpretation of data, drafting the article, or revising it critically for important intellectual content. Both authors read and approved the final manuscript.

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Correspondence to Felicity Goodyear-Smith.

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Goodyear-Smith, F., Schabetsberger, R. Gonococcus infection probably acquired from bathing in a natural thermal pool: a case report. J Med Case Reports 15, 458 (2021). https://0-doi-org.brum.beds.ac.uk/10.1186/s13256-021-03043-6

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